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KMID : 0377619730240010059
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Korean Jungang Medical Journal
1973 Volume.24 No. 1 p.59 ~ p.64
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The Use of Intra-amniotic PG F₂_(α) for Therapentic Termination of Pregnancy
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Kim, Syng Wook/金勝煜
Koh, Kyung Yong/高京龍
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Abstract
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The intra-amniotic administration of prostaglandin F2a has been tried for the therapeutic termination in 20 mid and third trimester pregnancies and following results were obtained.
1. Termination was achieved by single intra-amniotic administration of PG F2a 25mg. in 14 cases with the success "rate of 70 per cent. Additional 3 cases of pregnancy were terminated by repeated instillation of PG F2a, giving 85 per cent of corrected success rate.
2. Mean induction-termination interval was 12 hours 58 minutes in successful cases with single instillation.
3. Undesirable side effects, i.e, nausea, vomiting, diarrhea, fever and/or dizziness of mild degrees were observed in 7 cases.
4. No change has been observed in vital signs, blood count, blood chemistry and urinalysis before and after the instillation of PG F2a.
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